Expression Table

Gene Name: her9
Description: DNA binding
Key: I = Interpolated; X = Not Detected; ? = Inconsistent data; ! = Expressed but no region
Table built from ZFIN data (http://zfin.org/zf_info/downloads.html): Tue Dec 4 14:01:03 PST 2007

her9

Stage

Hours

ZFIN expression range

axis

shield

presumptive floor plate

neural plate

presumptive hypochord

notochord

somite

primary neuron

pronephric duct

pronephros

spinal cord

renal glomeruli

Zygote

1-cell

Cleavage

2-cell

0.75

4-cell

1.0

8-cell

1.25

16-cell

1.5

32-cell

1.75

64-cell

2.0

Blastula

124-cell

2.25

256-cell

2.5

512-cell

2.75

1k-cell

3.0

High

3.33

Oblong

3.66

Sphere

4.0

Dome

4.33

30% epiboly

4.66

Gastrula

50%-epiboly

5.25

Germ-ring

5.66

Shield

6.0

75% epiboly stage

8.0

90% epiboly

9.0

bud stage

10.0

Segmentation

1-4 somites

10.33

5-9 somites

11.66

10-13 somites

14.0

14-19 somites

16.0

20-25 somites

19.0

26+ somites

22.0

Pharyngula

Prim-5

24.0

Prim-15

30.0

Prim-25

36.0

High-pec

42.0

Hatching

Long-pec

48.0

Pec-fin

60.0

Literature Evidence

1. Mutant embryo and in-situ hybridization (or Q-PCR) showed the downstream target genes are affected
2. Overexpression of specific genes and in-situ hybridization (or Q-PCR) showed the downstream target genes are affected
3. Morpholino knock-down the expression of specific gene and in-situ hybridization (or Q-PCR) showed the downstream target genes are affected
4. The interaction sites of the input to downstream target genes have been identified by isolated the module and reporter assay (CAT, GFP, beta-galactosidase, leciferase or Q-PCR assay etc.)
5. The interaction sites of the input to downstream target genes have been identified by coinject the Morpholino or over-expression the genes for reporter assay (CAT, GFP, beta-galactosidase, leciferase or Q-PCR assay etc.)
6. The interaction sites of the input to downstream target genes have been identified by mutation the binding sites and reporter assay (CAT, GFP, beta-galactosidase, leciferase or Q-PCR assay etc.)

Evidence for Interaction Her9 expression in the pronephric duct at 17 ss is mildly down-regulated in notch1a mutants.

Target Gene her9

Upstream Gene notch1a

Interaction Type enhance

Altered model mutant embryos

Time of Interaction in evidence 16

Location of Interaction in evidence pronephric duct

Evidence for Direct 1

Binding Site Sequence

Location of Site

Last Author

Journal PLoS Genet

Year 2007

Vol 3

Start Page 133

Evidence for Interaction Her9 expression in the pronephric duct at 17 ss is mildly down-regulated in notch3-sp morphants.

Target Gene her9

Upstream Gene notch3

Interaction Type enhance

Altered model MASO

Time of Interaction in evidence 16

Location of Interaction in evidence pronephric duct

Evidence for Direct 3

Binding Site Sequence

Location of Site

Last Author

Journal PLoS Genet

Year 2007

Vol 3

Start Page 133

Evidence for Interaction	Her9 expression in the pronephric duct at 17 ss is mildly down-regulated in notch1a mutants.
Target Gene	her9
Upstream Gene	notch1a
Interaction Type	enhance
Altered model	mutant embryos
Time of Interaction in evidence	16
Location of Interaction in evidence	pronephric duct
Evidence for Direct	1
Binding Site Sequence
Location of Site
Last Author
Journal	PLoS Genet
Year	2007
Vol	3
Start Page	133