| gsn | Stage | Hours | ZFIN expression range | tail bud | central nervous system | notochord | trigeminal placode | somite | primary neuron | cranial ganglia | ganglion | neuron | eye | neural tube | olfactory placode | brain | forebrain | hindbrain | midbrain | primitive heart tube | proctodeum | heart | lateral line ganglion | retina | spinal cord | tegmentum | peripheral olfactory organ | retinal ganglion cell layer | whole organism | unspecified |
| Zygote | 1-cell | 0 | ||||||||||||||||||||||||||||
| Cleavage | 2-cell | 0.75 | X | |||||||||||||||||||||||||||
| 4-cell | 1.0 | X | ||||||||||||||||||||||||||||
| 8-cell | 1.25 | X | ||||||||||||||||||||||||||||
| 16-cell | 1.5 | X-I | ||||||||||||||||||||||||||||
| 32-cell | 1.75 | X-I | ||||||||||||||||||||||||||||
| 64-cell | 2.0 | X-I | ||||||||||||||||||||||||||||
| Blastula | 124-cell | 2.25 | X-I | |||||||||||||||||||||||||||
| 256-cell | 2.5 | X-I | ||||||||||||||||||||||||||||
| 512-cell | 2.75 | X-I | ||||||||||||||||||||||||||||
| 1k-cell | 3.0 | X-I | ||||||||||||||||||||||||||||
| High | 3.33 | X-I | ||||||||||||||||||||||||||||
| Oblong | 3.66 | X-I | ||||||||||||||||||||||||||||
| Sphere | 4.0 | X-I | ||||||||||||||||||||||||||||
| Dome | 4.33 | X-I | ||||||||||||||||||||||||||||
| 30% epiboly | 4.66 | X | X-I | |||||||||||||||||||||||||||
| Gastrula | 50%-epiboly | 5.25 | X | |||||||||||||||||||||||||||
| Germ-ring | 5.66 | X | ||||||||||||||||||||||||||||
| Shield | 6.0 | X | ||||||||||||||||||||||||||||
| 75% epiboly stage | 8.0 | X | ||||||||||||||||||||||||||||
| 90% epiboly | 9.0 | X | ||||||||||||||||||||||||||||
| bud stage | 10.0 | X | ||||||||||||||||||||||||||||
| Segmentation | 1-4 somites | 10.33 | ||||||||||||||||||||||||||||
| 5-9 somites | 11.66 | |||||||||||||||||||||||||||||
| 10-13 somites | 14.0 | |||||||||||||||||||||||||||||
| 14-19 somites | 16.0 | |||||||||||||||||||||||||||||
| 20-25 somites | 19.0 | I | I | ! | ! | ! | ! | |||||||||||||||||||||||
| 26+ somites | 22.0 | I | I | ! | ! | ! | ||||||||||||||||||||||||
| Pharyngula | Prim-5 | 24.0 | I | |||||||||||||||||||||||||||
| Prim-15 | 30.0 | I | I | I | I | I | ||||||||||||||||||||||||
| Prim-25 | 36.0 | |||||||||||||||||||||||||||||
| High-pec | 42.0 | I | I | I | ||||||||||||||||||||||||||
| Hatching | Long-pec | 48.0 | ||||||||||||||||||||||||||||
| Pec-fin | 60.0 | I | I | I |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin. |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | ectoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | ectoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin. |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | ectoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | ectoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the con |
| Target Gene | gsc |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | mesendoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | gsc |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | mesendoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the con |
| Target Gene | gsc |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | mesendoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | gsc |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | mesendoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | Vent mRNA was increased on the dorsal side of the gelsolin MO-injected embryo compared with the control embryo. |
| Target Gene | vent |
| Upstream Gene | gsn |
| Interaction Type | repress |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | margin |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | Vent mRNA was increased on the dorsal side of the gelsolin MO-injected embryo. |
| Target Gene | vent |
| Upstream Gene | gsn |
| Interaction Type | repress |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | margin |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin. |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | mesoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | mesoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin. |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | mesoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | mesoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the con |
| Target Gene | gsc |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | mesoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | gsc |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | mesoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the con |
| Target Gene | gsc |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | mesoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | gsc |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | mesoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin. |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | presumptive neural plate |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | presumptive neural plate |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin. |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | presumptive neural plate |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | presumptive neural plate |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the con |
| Target Gene | gsc |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | neuroectoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | gsc |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | neuroectoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the con |
| Target Gene | gsc |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | neuroectoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | gsc |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | neuroectoderm |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin. |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | presumptive brain |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | presumptive brain |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin. |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | presumptive brain |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |
| Evidence for Interaction | In situ hybridization showed that embryos injected with gelsolin mRNA up-regulated chordin and goosecoid transcripts. Conversely, gelsolin MO-injected embryos had lower intensity hybridization signals for chordin and goosecoid transcripts than did the co |
| Target Gene | chordin |
| Upstream Gene | gsn |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | presumptive brain |
| Evidence for Direct | 2, 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Joram Piatigorsky |
| Journal | PNAS |
| Year | 2003 |
| Vol | 100 |
| Start Page | 3287 |