| gbx2 | Stage | Hours | ZFIN expression range | hypoblast | neural plate | mesoderm | ectoderm | midbrain hindbrain boundary neural keel | midbrain neural rod | midbrain hindbrain boundary neural rod | neural tube | rhombomere 1 | diencephalon | pharyngeal arch | intermediate cell mass of mesoderm | otic vesicle | midbrain hindbrain boundary | lens | cerebellum | pectoral fin bud | caudal fin | retina | unspecified |
| Zygote | 1-cell | 0 | |||||||||||||||||||||
| Cleavage | 2-cell | 0.75 | I | I | |||||||||||||||||||
| 4-cell | 1.0 | I | I | ||||||||||||||||||||
| 8-cell | 1.25 | I | I | ||||||||||||||||||||
| 16-cell | 1.5 | I | I | ||||||||||||||||||||
| 32-cell | 1.75 | I | I | ||||||||||||||||||||
| 64-cell | 2.0 | I | I | ||||||||||||||||||||
| Blastula | 124-cell | 2.25 | I | I | |||||||||||||||||||
| 256-cell | 2.5 | I | I | ||||||||||||||||||||
| 512-cell | 2.75 | I | I | ||||||||||||||||||||
| 1k-cell | 3.0 | I | I | ||||||||||||||||||||
| High | 3.33 | ||||||||||||||||||||||
| Oblong | 3.66 | I | I | ||||||||||||||||||||
| Sphere | 4.0 | I | I | ||||||||||||||||||||
| Dome | 4.33 | I | I | ||||||||||||||||||||
| 30% epiboly | 4.66 | ||||||||||||||||||||||
| Gastrula | 50%-epiboly | 5.25 | I | I | |||||||||||||||||||
| Germ-ring | 5.66 | I | I | ||||||||||||||||||||
| Shield | 6.0 | ||||||||||||||||||||||
| 75% epiboly stage | 8.0 | ||||||||||||||||||||||
| 90% epiboly | 9.0 | I | |||||||||||||||||||||
| bud stage | 10.0 | ||||||||||||||||||||||
| Segmentation | 1-4 somites | 10.33 | I | I | |||||||||||||||||||
| 5-9 somites | 11.66 | I | I | ||||||||||||||||||||
| 10-13 somites | 14.0 | ||||||||||||||||||||||
| 14-19 somites | 16.0 | I | |||||||||||||||||||||
| 20-25 somites | 19.0 | I | I | I | |||||||||||||||||||
| 26+ somites | 22.0 | I | I | ||||||||||||||||||||
| Pharyngula | Prim-5 | 24.0 | |||||||||||||||||||||
| Prim-15 | 30.0 | I | I | I | |||||||||||||||||||
| Prim-25 | 36.0 | ||||||||||||||||||||||
| High-pec | 42.0 | I | I | I | |||||||||||||||||||
| Hatching | Long-pec | 48.0 | |||||||||||||||||||||
| Pec-fin | 60.0 |
| Evidence for Interaction | fgf8 mis-expression caused a pronounced dorsoventral expansion of gbx2 in the injected half. |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | epiblast |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | In wild-type embryos, fgf8 mis-expression caused a strong dorsalization of the whole embryo, which is visible as a pronounced dorsoventral expansion of spry4 and gbx2 in the injected half. |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | epiblast |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | In wild-type embryos, fgf8 mis-expression caused a strong dorsalization of the whole embryo, which is visible as a pronounced dorsoventral expansion of spry4 and gbx2 in the injected half. |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | epiblast |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | Gbx2 is lost in both the mesendodermal and the euroectodermal germ layer in fgf8 mutant embryos. |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | mesendoderm |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | Gbx2 is lost in both the mesendodermal and the euroectodermal germ layer in fgf8 mutant embryos. |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | neuroectoderm |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | fgf8 mis-expression caused a pronounced dorsoventral expansion of gbx2 in the injected half. |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | presumptive brain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | In wild-type embryos, fgf8 mis-expression caused a strong dorsalization of the whole embryo, which is visible as a pronounced dorsoventral expansion of spry4 and gbx2 in the injected half. |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | presumptive brain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | In wild-type embryos, fgf8 mis-expression caused a strong dorsalization of the whole embryo, which is visible as a pronounced dorsoventral expansion of spry4 and gbx2 in the injected half. |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 8 |
| Location of Interaction in evidence | presumptive brain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | Onset of gbx2 expression is affected in the ace mutant, albeit in a different way. In ace mutants, expression of gbx2 is already absent at 90% of epiboly. |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 9 |
| Location of Interaction in evidence | ectoderm |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Mechanisms of Development |
| Year | 2003 |
| Vol | 120 |
| Start Page | 919 |
| Evidence for Interaction | In ace mutant s(fgf8 mutant) , gbx2 expression is already absent at 90% of epiboly. gbx1 expression is rescued by wild type cell transplantation into ace mutant |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 9 |
| Location of Interaction in evidence | ectoderm |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Mechanisms of Development |
| Year | 2003 |
| Vol | 120 |
| Start Page | 919 |
| Evidence for Interaction | In ace mutant s(fgf8 mutant) , gbx2 expression is already absent at 90% of epiboly. gbx1 expression is rescued by wild type cell transplantation into ace mutant |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 9 |
| Location of Interaction in evidence | ectoderm |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Mechanisms of Development |
| Year | 2003 |
| Vol | 120 |
| Start Page | 919 |
| Evidence for Interaction | Gbx2 is lost in both the mesendodermal and the euroectodermal germ layer in ace mutant embryos. |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 9 |
| Location of Interaction in evidence | mesendoderm |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | Gbx2 is lost in both the mesendodermal and the euroectodermal germ layer in ace mutant embryos. |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 9 |
| Location of Interaction in evidence | mesendoderm |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | At 100% of epiboly, gbx2 expression is seen only in the endomesodermal and disappear in endoderm and ectoderm in spg mutants. |
| Target Gene | gbx2 |
| Upstream Gene | pou5f1 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 9 |
| Location of Interaction in evidence | mesendoderm |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Mechanisms of Development |
| Year | 2003 |
| Vol | 120 |
| Start Page | 919 |
| Evidence for Interaction | At 100% of epiboly, gbx2 expression is seen only in the endomesodermal and disappear in endoderm and ectoderm in spg mutants. |
| Target Gene | gbx2 |
| Upstream Gene | pou5f1 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 9 |
| Location of Interaction in evidence | mesendoderm |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Mechanisms of Development |
| Year | 2003 |
| Vol | 120 |
| Start Page | 919 |
| Evidence for Interaction | Gbx2 is lost in both the mesendodermal and the euroectodermal germ layer in ace mutant embryos. |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 9 |
| Location of Interaction in evidence | neuroectoderm |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | Gbx2 is lost in both the mesendodermal and the euroectodermal germ layer in ace mutant embryos. |
| Target Gene | gbx2 |
| Upstream Gene | fgf8 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 9 |
| Location of Interaction in evidence | neuroectoderm |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | In mutant embryos, the mesendodermal domain of gbx2 is initiated normally but the neurectodermal domain. |
| Target Gene | gbx2 |
| Upstream Gene | pou5f1 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 9 |
| Location of Interaction in evidence | neurectoderm |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | In mutant embryos, the mesendodermal domain of gbx2 is initiated normally but the neurectodermal domain. |
| Target Gene | gbx2 |
| Upstream Gene | pou5f1 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 9 |
| Location of Interaction in evidence | neurectoderm |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Development |
| Year | 2002 |
| Vol | 129 |
| Start Page | 917 |
| Evidence for Interaction | At 100% of epiboly, gbx2 expression is seen only in the endomesodermal and disappear in endoderm and ectoderm in spg mutants. |
| Target Gene | gbx2 |
| Upstream Gene | pou5f1 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 9 |
| Location of Interaction in evidence | presumptive otic |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Mechanisms of Development |
| Year | 2003 |
| Vol | 120 |
| Start Page | 919 |
| Evidence for Interaction | At 100% of epiboly, gbx2 expression is seen only in the endomesodermal and disappear in endoderm and ectoderm in spg mutants. |
| Target Gene | gbx2 |
| Upstream Gene | pou5f1 |
| Interaction Type | enhance |
| Altered model | mutant embryos |
| Time of Interaction in evidence | 9 |
| Location of Interaction in evidence | presumptive otic |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Mechanisms of Development |
| Year | 2003 |
| Vol | 120 |
| Start Page | 919 |
| Evidence for Interaction | The expression of otx2 in the prospective forebrain and midbrain of the gbx2 injected embryos was severely down-regulated |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | six3 expression in the anterior forebrain embryos was also drastically repressed |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of otx2 in the prospective forebrain and midbrain of the gbx2 injected embryos was severely down-regulated |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of otx2 in the prospective forebrain and midbrain of the gbx2 injected embryos was severely down-regulated |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | During gastrula stages, three parallel pathways (Pax,Wnt and Fgf) are activated around the otx2/gbx1 interface in response to patterning signals. Towards the end of gastrulation, spg ( pou2) expression refines to theMHB territory.At the end of gastrulatio |
| Target Gene | gbx2 |
| Upstream Gene | otx2 |
| Interaction Type | enhance |
| Altered model | response to patterning signals |
| Time of Interaction in evidence | 10 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Mechanisms of Development |
| Year | 2003 |
| Vol | 120 |
| Start Page | 919 |
| Evidence for Interaction | During gastrula stages, three parallel pathways (Pax,Wnt and Fgf) are activated around the otx2/gbx1 interface in response to patterning signals. Towards the end of gastrulation, spg ( pou2) expression refines to theMHB territory.At the end of gastrulatio |
| Target Gene | gbx2 |
| Upstream Gene | otx2 |
| Interaction Type | enhance |
| Altered model | response to patterning signals |
| Time of Interaction in evidence | 10 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Mechanisms of Development |
| Year | 2003 |
| Vol | 120 |
| Start Page | 919 |
| Evidence for Interaction | During gastrula stages, three parallel pathways (Pax,Wnt and Fgf) are activated around the otx2/gbx1 interface in response to patterning signals. Towards the end of gastrulation, spg ( pou2) expression refines to theMHB territory.At the end of gastrulatio |
| Target Gene | gbx2 |
| Upstream Gene | gbx1 |
| Interaction Type | enhance |
| Altered model | response to patterning signals |
| Time of Interaction in evidence | 10 |
| Location of Interaction in evidence | neuroectoderm |
| Evidence for Direct | 1 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Michael Brand |
| Journal | Mechanisms of Development |
| Year | 2003 |
| Vol | 120 |
| Start Page | 919 |
| Evidence for Interaction | six3 expression in the anterior forebrain embryos was also drastically repressed |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10 |
| Location of Interaction in evidence | optic stalk |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, shha was suppressed. |
| Target Gene | shha |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | ventral diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, shha was suppressed. |
| Target Gene | shha |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | ventral diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, six3a was suppressed. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, six3a was suppressed. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The eng2 expression at the prospective MHB was abrogated in the Gbx overexpress embryo. MO-gbx2 down-regulation of eng2 (40%, n= 28 ) was observed in some of the embryos. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Downregulation of wnt1 and eng2 was observed in MO-gbx2 injected embryos. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Downregulation of wnt1 and eng2 was observed in MO-gbx2 injected embryos. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Down-regulation of fgf8 was observed in fgf8 morphant. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, six3a was suppressed. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, six3a was suppressed. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, six3a was suppressed. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, six3a was suppressed. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The six3 expression was suppressed in the prospective anterior forebrain of the injected embryos. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression level of six3 were not affected by MO-gbx2. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, wnt1 was suppressed. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Downregulation of wnt1 and eng2 was observed in MO-gbx2 injected embryos. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, wnt1 was suppressed. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Downregulation of wnt1 and eng2 was observed in MO-gbx2 injected embryos. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In gbx2 expression embryos, the expression of wnt1 in the future posterior midbrain was abrogated. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The eng2 expression at the prospective MHB was abrogated in the Gbx overexpress embryo. MO-gbx2 down-regulation of eng2 (40%, n= 28 ) was observed in some of the embryos. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Downregulation of wnt1 and eng2 was observed in MO-gbx2 injected embryos. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Downregulation of wnt1 and eng2 was observed in MO-gbx2 injected embryos. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Down-regulation of fgf8 was observed in fgf8 morphant. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, six3a was suppressed. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, six3a was suppressed. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, six3a was suppressed. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, six3a was suppressed. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The six3 expression was suppressed in the prospective anterior forebrain of the injected embryos. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression level of six3 were not affected by MO-gbx2. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, wnt1 was suppressed. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Downregulation of wnt1 and eng2 was observed in MO-gbx2 injected embryos. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, wnt1 was suppressed. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Downregulation of wnt1 and eng2 was observed in MO-gbx2 injected embryos. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In gbx2 expression embryos, the expression of wnt1 in the future posterior midbrain was abrogated. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The eng2 expression at the prospective MHB was abrogated in the Gbx overexpress embryo. MO-gbx2 down-regulation of eng2 (40%, n= 28 ) was observed in some of the embryos. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Downregulation of wnt1 and eng2 was observed in MO-gbx2 injected embryos. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Downregulation of wnt1 and eng2 was observed in MO-gbx2 injected embryos. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Down-regulation of fgf8 was observed in fgf8 morphant. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, six3a was suppressed. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, six3a was suppressed. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression levels of otx2, six3a, pax2.1, fgf8, and krox20 were not affected by MO-gbx2. |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The six3 expression was suppressed in the prospective anterior forebrain of the injected embryos. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | At the three-somite stage, the expression level of six3 were not affected by MO-gbx2. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | natural |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, wnt1 was suppressed. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Downregulation of wnt1 and eng2 was observed in MO-gbx2 injected embryos. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, wnt1 was suppressed. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | Downregulation of wnt1 and eng2 was observed in MO-gbx2 injected embryos. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | enhance |
| Altered model | MASO |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 3 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In gbx2 expression embryos, the expression of wnt1 in the future posterior midbrain was abrogated. |
| Target Gene | wnt1 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 10.33 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The six3 expression was suppressed in the prospective anterior forebrain of the injected embryos. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 11.66 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The six3 expression was suppressed in the prospective anterior forebrain of the injected embryos. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 11.66 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The six3 expression was suppressed in the prospective anterior forebrain of the injected embryos. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 11.66 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 14 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 14 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 14 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 14 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 14 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 14 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 19 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 19 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 19 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 19 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 19 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 19 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | fgf8 expression in the anterior portion of the hindbrain was essentially intact, although it was downregulated in the dorsal telencephalon and anterior diencephalon. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, fgf8 was suppressed. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, fgf8 was suppressed. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of otx2 in the diencephalon and midbrain of the gbx2 injected embryos was decreased. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of sonic hedgehog (shh) was suppressed in the ventral diencephalon but was unaffected in the floor plate of the hindbrain and spinal cord. |
| Target Gene | shha |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | ventral diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of Gbx2 in the anterior forebrain of the injected embryos was decreased. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of otx2 in the diencephalon and midbrain of the gbx2 injected embryos was decreased. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of Gbx2 in the anterior forebrain of the injected embryos was decreased. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of otx2 in the diencephalon and midbrain of the gbx2 injected embryos was decreased. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, pax2a was suppressed. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, pax2a was suppressed. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of wnt1 in the dorsal midbrain and in the posterior ring-like region of the midbrain and those of eng2 and pax2.1 at the MHB were abrogated. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of wnt1 in the dorsal midbrain and in the posterior ring-like region of the midbrain and those of eng2 and pax2.1 at the MHB were abrogated. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of Gbx2 in the anterior forebrain of the injected embryos was decreased. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, pax2a was suppressed. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, pax2a was suppressed. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of wnt1 in the dorsal midbrain and in the posterior ring-like region of the midbrain and those of eng2 and pax2.1 at the MHB were abrogated. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of wnt1 in the dorsal midbrain and in the posterior ring-like region of the midbrain and those of eng2 and pax2.1 at the MHB were abrogated. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | fgf8 expression in the anterior portion of the hindbrain was essentially intact, although it was downregulated in the dorsal telencephalon and anterior diencephalon. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | telencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, fgf8 was suppressed. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | telencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, fgf8 was suppressed. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 24 |
| Location of Interaction in evidence | telencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | six3 expression in the anterior forebrain embryos was also drastically repressed |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 26 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | six3 expression in the anterior forebrain embryos was also drastically repressed |
| Target Gene | six3a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 26 |
| Location of Interaction in evidence | optic stalk |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, fgf8 was suppressed. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, fgf8 was suppressed. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of sonic hedgehog (shh) was suppressed in the ventral diencephalon but was unaffected in the floor plate of the hindbrain and spinal cord. |
| Target Gene | shha |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | ventral diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of Gbx2 in the anterior forebrain of the injected embryos was decreased. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | diencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of Gbx2 in the anterior forebrain of the injected embryos was decreased. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | forebrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, otx2 was suppressed. |
| Target Gene | otx2 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, pax2a was suppressed. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, pax2a was suppressed. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of wnt1 in the dorsal midbrain and in the posterior ring-like region of the midbrain and those of eng2 and pax2.1 at the MHB were abrogated. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of wnt1 in the dorsal midbrain and in the posterior ring-like region of the midbrain and those of eng2 and pax2.1 at the MHB were abrogated. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of Gbx2 in the anterior forebrain of the injected embryos was decreased. |
| Target Gene | six3b |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | midbrain |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, eng2a was suppressed. |
| Target Gene | eng2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, pax2a was suppressed. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, pax2a was suppressed. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of wnt1 in the dorsal midbrain and in the posterior ring-like region of the midbrain and those of eng2 and pax2.1 at the MHB were abrogated. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | The expression of wnt1 in the dorsal midbrain and in the posterior ring-like region of the midbrain and those of eng2 and pax2.1 at the MHB were abrogated. |
| Target Gene | pax2a |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | MHB |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, fgf8 was suppressed. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | telencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |
| Evidence for Interaction | In the embryos injected gbx2 mRNA data, fgf8 was suppressed. |
| Target Gene | fgf8 |
| Upstream Gene | gbx2 |
| Interaction Type | repress |
| Altered model | overexpression |
| Time of Interaction in evidence | 28 |
| Location of Interaction in evidence | telencephalon |
| Evidence for Direct | 2 |
| Binding Site Sequence | |
| Location of Site | |
| Last Author | Kyo Yamasu |
| Journal | Developmental Dynamics |
| Year | 2003 |
| Vol | 228 |
| Start Page | 433 |