Expression Table

Gene Name: gadd45bl
Description: response to methylmercury
Key: I = Interpolated; X = Not Detected; ? = Inconsistent data; ! = Expressed but no region
Table built from ZFIN data (http://zfin.org/zf_info/downloads.html): Tue Dec 4 14:01:03 PST 2007

gadd45bl

Stage

Hours

ZFIN expression range

YSL

margin

presumptive segmental plate

segmental plate

neural crest

somite

musculature system

lens

whole organism

Zygote

1-cell

Cleavage

2-cell

0.75

4-cell

1.0

8-cell

1.25

16-cell

1.5

32-cell

1.75

64-cell

2.0

Blastula

124-cell

2.25

256-cell

2.5

512-cell

2.75

1k-cell

3.0

High

3.33

Oblong

3.66

Sphere

4.0

Dome

4.33

30% epiboly

4.66

Gastrula

50%-epiboly

5.25

Germ-ring

5.66

Shield

6.0

75% epiboly stage

8.0

90% epiboly

9.0

bud stage

10.0

Segmentation

1-4 somites

10.33

5-9 somites

11.66

10-13 somites

14.0

14-19 somites

16.0

20-25 somites

19.0

26+ somites

22.0

Pharyngula

Prim-5

24.0

Prim-15

30.0

Prim-25

36.0

High-pec

42.0

Hatching

Long-pec

48.0

Pec-fin

60.0

Literature Evidence

1. Mutant embryo and in-situ hybridization (or Q-PCR) showed the downstream target genes are affected
2. Overexpression of specific genes and in-situ hybridization (or Q-PCR) showed the downstream target genes are affected
3. Morpholino knock-down the expression of specific gene and in-situ hybridization (or Q-PCR) showed the downstream target genes are affected
4. The interaction sites of the input to downstream target genes have been identified by isolated the module and reporter assay (CAT, GFP, beta-galactosidase, leciferase or Q-PCR assay etc.)
5. The interaction sites of the input to downstream target genes have been identified by coinject the Morpholino or over-expression the genes for reporter assay (CAT, GFP, beta-galactosidase, leciferase or Q-PCR assay etc.)
6. The interaction sites of the input to downstream target genes have been identified by mutation the binding sites and reporter assay (CAT, GFP, beta-galactosidase, leciferase or Q-PCR assay etc.)

Evidence for Interaction Expression of mesp-a and her1 in the anterior PSM and segmental expression of MyoD and fgf8 in the somites were disorganized in the GADD45?1-MO GADD45?2-MO-injected embryos.

Target Gene mespa

Upstream Gene gadd45bl

Interaction Type enhance

Altered model MASO

Time of Interaction in evidence 11.66

Location of Interaction in evidence somite

Evidence for Direct 3

Binding Site Sequence

Location of Site

Last Author Igor B. Dawid

Journal PNAS

Year 2004

Vol 102

Start Page 361

Evidence for Interaction	Expression of mesp-a and her1 in the anterior PSM and segmental expression of MyoD and fgf8 in the somites were disorganized in the GADD45?1-MO GADD45?2-MO-injected embryos.
Target Gene	mespa
Upstream Gene	gadd45bl
Interaction Type	enhance
Altered model	MASO
Time of Interaction in evidence	11.66
Location of Interaction in evidence	somite
Evidence for Direct	3
Binding Site Sequence
Location of Site
Last Author	Igor B. Dawid
Journal	PNAS
Year	2004
Vol	102
Start Page	361