| dbx1a | |||||||||||||||||||||||||||||
| Type | Gene1 | Effect | Gene2 | Sentence | Perturbation methods | Time of Interaction in evidence | territories of interaction or Tissue | Evidence for Direct | Authors | Journal | PubYear | Volume | Pages | MedLine Reference | Connectivity | # of References | Found In Pathways | Journal Link | Journal Reference | Mechanism | URN | ISSN | Issue | LocatorString | MedlineTA | PubMonth | p-value [Evol. Bioinformatics 2007:3(197)] | TextPath | Title |
| Expression | dbx1a | positive | dlx2a | Induction of prethalamic dlx2a expression thus requires less overall Hh signalling from the ZLI compared with thalamic dbx1a. | 2 | 1 | Zebrafish_shhb_20080729 | urn:agi-Expression:inout-urn:agi-llid:120237:out-urn:agi-llid:1746::positive | digtext:http://www.ncbi.nlm.nih.gov/entrez/utils/fref.fcgi?PrId=3051&itool=AbstractPlus-def&uid=16452095&db=pubmed&url=http://dev.biologists.org/cgi/pmidlookup?view=long&pmid=16452095 | ||||||||||||||||||||
| Expression | dbx1a | negative | nkx6.2 | This finding is the first evidence that dbx1 antagonizes nkx6.2 expression, suggesting that these genes are cross-repressive partners (Fig. 8B). | 2 | 1 | Zebrafish_dbx1a_20080728 | urn:agi-Expression:inout-urn:agi-llid:120237:out-urn:agi-llid:84504::negative | digtext:http://www3.interscience.wiley.com/blank.html | ||||||||||||||||||||
| Expression | msxe | negative | dbx1a | Previous work has shown that Msx1/2 homeodomain proteins can repress Dbx gene expression (Timmer et al.,[2002]). | 2 | 1 | Zebrafish_dbx1a_20080728 | urn:agi-Expression:inout-urn:agi-llid:4487:out-urn:agi-llid:120237::negative | digtext:http://www3.interscience.wiley.com/blank.html | ||||||||||||||||||||
| Expression | nomo | negative | dbx1a | The expression of anterior mesendodermal markers (gsc: presumptive hatching glandþprechordal plate; hgg1: presumptive hatching gland; hlx1: prechordal plate) is enlarged in injected embryos, while znot expression in the anterior notochordal domain is abse | blocking the production of protein | 10 | hypoblast | 3 | Christian Haass | The EMBO Journal | 2004 | 23 | 3041 | ||||||||||||||||
| Expression | oep | positive | dbx1a | Expression of goosecoid is initiated but not maintained in oep mutants. | mutant embryos | 10 | mesoderm | 1 | Wolfgang Driever | Development | 1997 | 124 | 327 | ||||||||||||||||
| Expression | ra | neutral | dbx1a | Low levels of BMP are also important to position the dorsal boundary of Dbx expression (Timmer et al.,[2002]), and RA is required in an unknown way to allow Dbx expression, possibly by antagonizing these dorsal signals (Pierani et al.,[1999]; Novitch et a | 2 | 1 | Zebrafish_dbx1a_20080728 | urn:agi-Expression:inout-urn:agi-cas:302-79-4:out-urn:agi-llid:120237::unknown | digtext:http://www3.interscience.wiley.com/blank.html | ||||||||||||||||||||
| Expression | ra | positive | dbx1a | Because RA has previously been shown to induce Dbx expression in neural explants, we analyzed expression at both 18 hpf and 24 hpf. | 2 | 1 | Zebrafish_dbx1a_20080728 | urn:agi-Expression:inout-urn:agi-cas:302-79-4:out-urn:agi-llid:120237::positive | digtext:http://www3.interscience.wiley.com/blank.html | ||||||||||||||||||||
| Expression | shha | negative | dbx1a | Injection of shh mRNA into wild-type embryos resulted in over-expression of sox4b in the pancreatic region, as previously described for endocrine genes. | overexpression | 30 | midbrain | 2 | Thomas Gerster | Development | 1996 | 122 | 1769 | ||||||||||||||||